Slide 26 of 28
Part 4 — PreventionSlide 26
Slide 26 · The Mitigation Matrix
Which mitigation stops which scenario — and which ones provide the widest coverage
Scenario MIT01
Provenance/SBOM
MIT02
Allowlist/Pin
MIT03
Sandbox
MIT04
Secure Prompts
MIT05
mTLS/PKI
MIT06
Continuous Val.
MIT07
Hash Pin
MIT08
Kill Switch
MIT09
Zero Trust
S1: Amazon Q VS Code — Compromised update
S2: GitHub MCP tool descriptor poisoning
S3: Postmark MCP impersonator on npm
S4: AgentSmith prompt-hub proxy
S5: Poisoned nx/debug npm — coding agent
S6: Agent-in-the-Middle via agent cards
Legend — Directly addresses Partially mitigates Not applicable

MIT02 (Allowlist/Pin) and MIT08 (Kill Switch) cover all six scenarios — together they form the core of agentic supply chain defense. MIT06 (Continuous Validation) and MIT07 (Hash Pinning) are the next-widest controls. MIT05 (mTLS/PKI) addresses the four scenarios involving agent-to-agent trust. MIT03 (Sandbox) limits blast radius across all runtime execution scenarios.

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